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In another aspect, the invention relates to the pharmaceutical composition of the invention for use in the treatment and/or prevention of an adrenoleukodystrophy

Arthritis Rheum (2008) 58:387383

Beyond central adaptations, endurance training promotes peripheral remodeling, including increased mitochondrial content and capillary density in skeletal muscle, thereby improving oxygen extraction and utilization during exercise (61)

Later, Hornig and colleagues also suggested disturbed IL-1 signaling and autoimmunity-type patterns of immune activation while analyzing the cerebrospinal fluid in patients with atypical clinical characteristics (Hornig et al